close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM3633Putative bacterial regulatory protein; lacI family; similar to E. coli regulator for rbs operon (AAC76776.1); Blastp hit to AAC76776.1 (330 aa), 27% identity in aa 2 - 304. (335 aa)    
Predicted Functional Partners:
leuC2
Putative 3-isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
    
 
 0.883
fruR
Transcriptional repressor of fru operon and others; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism.
  
   
 0.818
treR
Transcriptional repressor of treABC; Repressor of the treBC operon. It is able to bind trehalose- 6-phosphate.
  
  
 0.810
STM3696
Similar to E. coli L-idonate transcriptional regulator (AAC77221.1); Blastp hit to AAC77221.1 (332 aa), 30% identity in aa 7 - 326.
  
    0.776
galR
Transcriptional repressor of galETK operon; Repressor of the galactose operon. Binds galactose as an inducer (By similarity).
  
     0.775
mnmC
Putative peptidase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.
      
 0.770
moeA
Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP; Belongs to the MoeA family.
      
 0.700
ptsA
General PTS family enzyme I; Similar to E. coli PEP-protein phosphotransferase system enzyme I (AAC76929.1); Blastp hit to AAC76929.1 (711 aa), 90% identity in aa 1 - 711.
   
 
 0.612
gltB
Similar to E. coli glutamate synthase, large subunit (AAC76244.1); Blastp hit to AAC76244.1 (1517 aa), 95% identity in aa 32 - 1517.
    
 
 0.593
STM3632
Putative PQQ enzyme repeat protein.
  
   0.579
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.