Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yiaKPutative malate dehydrogenase; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate. (332 aa)    
Predicted Functional Partners:
lyxK
Similar to E. coli L-xylulose kinase, cryptic (AAC76604.1); Blastp hit to AAC76604.1 (498 aa), 85% identity in aa 1 - 498.
 
 
 0.973
yiaL
Putative cytoplasmic protein; Similar to E. coli putative lipase (AAC76600.1); Blastp hit to AAC76600.1 (155 aa), 82% identity in aa 1 - 154.
 
  
 0.957
yfeH
Putative Na+-dependent transporter; Similar to E. coli putative cytochrome oxidase (AAC75463.1); Blastp hit to AAC75463.1 (332 aa), 90% identity in aa 1 - 332.
   
    0.941
yiaM
Putative transporter; Similar to E. coli orf, hypothetical protein (AAC76601.1); Blastp hit to AAC76601.1 (157 aa), 76% identity in aa 1 - 157.
 
  
 0.867
yiaO
Similar to E. coli putative solute-binding transport protein (AAC76603.1); Blastp hit to AAC76603.1 (328 aa), 87% identity in aa 1 - 328.
 
  
 0.865
sgbU
Similar to E. coli probable 3-hexulose-6-phosphate isomerase (AAC76606.1); Blastp hit to AAC76606.1 (297 aa), 91% identity in aa 12 - 297.
  
  
 0.850
yiaN
Similar to E. coli putative membrane protein (AAC76602.1); Blastp hit to AAC76602.1 (424 aa), 90% identity in aa 1 - 398.
  
  
 0.824
sgbH
Putative 3-hexulose-6-phosphate isomerase; Similar to E. coli probable 3-hexulose 6-phosphate synthase (AAC76605.1); Blastp hit to AAC76605.1 (220 aa), 90% identity in aa 1 - 220.
     
 0.810
yhiP
Putative POT family peptide transport protein; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily.
      
 0.750
rspA
Putative dehydratase; Similar to E. coli starvation sensing protein (AAC74653.1); Blastp hit to AAC74653.1 (404 aa), 94% identity in aa 1 - 404.
  
  
 0.747
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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