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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yiaLPutative cytoplasmic protein; Similar to E. coli putative lipase (AAC76600.1); Blastp hit to AAC76600.1 (155 aa), 82% identity in aa 1 - 154. (154 aa)    
Predicted Functional Partners:
yiaK
Putative malate dehydrogenase; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
 
  
 0.955
sgbU
Similar to E. coli probable 3-hexulose-6-phosphate isomerase (AAC76606.1); Blastp hit to AAC76606.1 (297 aa), 91% identity in aa 12 - 297.
 
  
 0.954
sgbH
Putative 3-hexulose-6-phosphate isomerase; Similar to E. coli probable 3-hexulose 6-phosphate synthase (AAC76605.1); Blastp hit to AAC76605.1 (220 aa), 90% identity in aa 1 - 220.
 
   
 0.950
yiaM
Putative transporter; Similar to E. coli orf, hypothetical protein (AAC76601.1); Blastp hit to AAC76601.1 (157 aa), 76% identity in aa 1 - 157.
 
  
 0.949
yiaO
Similar to E. coli putative solute-binding transport protein (AAC76603.1); Blastp hit to AAC76603.1 (328 aa), 87% identity in aa 1 - 328.
  
  
 0.949
yiaN
Similar to E. coli putative membrane protein (AAC76602.1); Blastp hit to AAC76602.1 (424 aa), 90% identity in aa 1 - 398.
  
  
 0.945
yiaJ
IclR family transcriptional repressor; Similar to E. coli putative regulator (AAC76598.1); Blastp hit to AAC76598.1 (282 aa), 91% identity in aa 16 - 276.
  
  
 0.910
sgbE
L-ribulose-5-phosphate 4-epimerase; Similar to E. coli putative epimerase/aldolase (AAC76607.1); Blastp hit to AAC76607.1 (231 aa), 93% identity in aa 1 - 231.
     
 0.894
lyxK
Similar to E. coli L-xylulose kinase, cryptic (AAC76604.1); Blastp hit to AAC76604.1 (498 aa), 85% identity in aa 1 - 498.
  
  
 0.884
yeiE
Similar to E. coli putative transcriptional regulator LYSR-type (AAC75218.1); Blastp hit to AAC75218.1 (293 aa), 91% identity in aa 1 - 287; Belongs to the LysR transcriptional regulatory family.
      
 0.800
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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