Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sadBPutative inner membrane lipoprotein; Required for proper surface expression of the autotransporter adhesin SadA. Could be directly involved in the biogenesis of functionally active SadA. (227 aa)    
Predicted Functional Partners:
sadA
Putative inner membrane protein; Involved in cell aggregation, biofilm formation, and adhesion to human intestinal epithelial cells; Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
     
 0.981
yaiI
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73490.1); Blastp hit to AAC73490.1 (192 aa), 89% identity in aa 41 - 191; Belongs to the UPF0178 family.
      
 0.896
ybaK
Putative cytoplasmic protein; Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity.
      
 0.850
yggU
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75990.1); Blastp hit to AAC75990.1 (100 aa), 90% identity in aa 5 - 98; Belongs to the UPF0235 family.
      
 0.780
STM3600
Putative sugar kinases; Ribokinase family; similar to E. coli putative kinase (AAC76399.1); Blastp hit to AAC76399.1 (261 aa), 30% identity in aa 7 - 261.
   
  
 0.773
preT
Putative NADPH-dependent glutamate synthase beta chain or related oxidoreductase; Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity).
      
 0.703
yffB
Putative glutaredoxin family protein; Similar to E. coli orf, hypothetical protein (AAC75524.1); Blastp hit to AAC75524.1 (118 aa), 80% identity in aa 1 - 118; Belongs to the ArsC family.
      
 0.646
ybaD
Putative transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
      
 0.407
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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