Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
lldPLctP transporter; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force (By similarity). (551 aa)    
Predicted Functional Partners:
lldR
Putative transcriptional GntR family regulator for lct operon; Similar to E. coli transcriptional regulator (AAC76628.1); Blastp hit to AAC76628.1 (258 aa), 86% identity in aa 1 - 258.
  
 0.999
lldD
L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
  
 0.997
dld
NADH independent D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.
 
  
 0.932
ydiJ
Similar to E. coli putative oxidase (AAC74757.1); Blastp hit to AAC74757.1 (1018 aa), 88% identity in aa 1 - 1017.
  
  
 0.796
ybdD
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77309.1); Blastp hit to AAC77309.1 (67 aa), 73% identity in aa 1 - 67.
      
 0.706
aspC
Similar to E. coli aspartate aminotransferase (AAC74014.1); Blastp hit to AAC74014.1 (396 aa), 95% identity in aa 1 - 396; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
      
 0.677
yibK
Putative tRNA/rRNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
  
    0.622
nifJ
Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174.
     
 0.607
glpC
Similar to E. coli sn-glycerol-3-phosphate dehydrogenase (anaerobic), K-small subunit (AAC75303.1); Blastp hit to AAC75303.1 (396 aa), 94% identity in aa 1 - 395.
 
  
 0.587
pdhR
Transcriptional repressor for pyruvate dehydrogenase complex (GntR family); Transcriptional repressor for the pyruvate dehydrogenase complex genes aceEF and lpd.
  
 0.568
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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