STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
cysESerine acetyltransferase. (SW:CYSE_SALTY); Belongs to the transferase hexapeptide repeat family. (273 aa)    
Predicted Functional Partners:
cysK
Subunit of cysteine synthase A and O-acetylserine sulfhydrolase A; Two cysteine synthase enzymes are found, this enzyme and CysM; both catalyze the same reaction. Cysteine synthase B (CysM) can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product.
 
 0.999
cysM
Cysteine synthase B; Two cysteine synthase enzymes are found. Both catalyze the same reaction. Cysteine synthase B can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product.
 
 0.997
STM0458
Putative cysteine synthase/cystathionine beta-synthase; Similar to E. coli cysteine synthase B, O-acetylserine sulfhydrolase B (AAC75474.1); Blastp hit to AAC75474.1 (303 aa), 26% identity in aa 6 - 207, 35% identity in aa 198 - 289.
  
 0.963
cysS
Similar to E. coli cysteine tRNA synthetase (AAC73628.1); Blastp hit to AAC73628.1 (461 aa), 94% identity in aa 1 - 461; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.960
gpsA
Glycerol-3-phosphate dehydrogenase [NAD+]. (SW:GPDA_SALTY); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.924
cysB
Transcriptional regulator for cysteine regulon; This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription.
  
   
 0.908
sdaA
Similar to E. coli L-serine deaminase (AAC74884.1); Blastp hit to AAC74884.1 (454 aa), 94% identity in aa 1 - 454; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.902
STM2196
Putative D-serine dehydratase; Similar to E. coli L-serine deaminase (AAC74884.1); Blastp hit to AAC74884.1 (454 aa), 48% identity in aa 1 - 452; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.902
sdaB
Similar to E. coli L-serine dehydratase (deaminase), L-SD2 (AAC75839.1); Blastp hit to AAC75839.1 (455 aa), 94% identity in aa 1 - 455; L-threonine deaminase 2; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.902
tdcG
Similar to E. coli L-serine dehydratase (deaminase), L-SD2 (AAC75839.1); Blastp hit to AAC75839.1 (455 aa), 74% identity in aa 1 - 452; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.902
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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