Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rfaGSimilar to E. coli glucosyltransferase I; lipopolysaccharide core biosynthesis (AAC76655.1); Blastp hit to AAC76655.1 (374 aa), 86% identity in aa 1 - 374. (374 aa)    
Predicted Functional Partners:
rfaP
Lipopolysaccharide core biosynthesis protein; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core.
 
 0.999
rfaQ
Modification of heptose region of core; similar to E. coli lipopolysaccharide core biosynthesis (AAC76656.1); Blastp hit to AAC76656.1 (344 aa), 78% identity in aa 1 - 344.
 
  
 0.996
rfaB
UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Adds a galactose goup to a glucose group of LPS; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
 
  
 0.988
rfaI
UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase; Adds the galactose(I) group on the glucose(I) group of LPS.
 
  
 0.983
rfaF
ADP-heptose; AFP-heptose--lps heptosyltransferase II. (SW:RFAF_SALTY).
 
 
 0.981
rfaJ
UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase; Adds the glucose(II) group on the galactose(I) group of LPS.
 
  
 0.975
rfaC
Heptosyl transferase I; Heptose transfer to the lipopolysaccharide core. It transfers the innermost heptose to [4'-P](3-deoxy-D-manno-octulosonic acid)2-IVA; Belongs to the glycosyltransferase 9 family.
 
  
 0.954
rfaZ
Lipopolysaccharide core biosynthesis protein RFAZ. (SW:RFAZ_SALTY).
  
  
 0.912
rfaL
O-antigen ligase; Adds the O-antigen on the glucose(II) group of LPS.
  
  
 0.898
rfaD
ADP-L-glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
  
  
 0.895
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (20%) [HD]