Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rmbAPutative cytoplasmic protein; Pathogenicity island encoded protein: SPI3; RmbA (gi|4324609). (205 aa)    
Predicted Functional Partners:
misL
Putative autotransported protein; Pathogenicity island encoded protein: SPI3; MisL (gi|4324610).
  
  
 0.887
ttrB
Tetrathionate reductase complex, subunit B; Part of a membrane-bound tetrathionate reductase that catalyzes the reduction of tetrathionate to thiosulfate. TtrB is probably involved in transfer of electrons from TtrC to TtrA. During mice infection, the ability to use tetrathionate as an electron acceptor is a growth advantage for S.typhimurium over the competing microbiota in the lumen of the inflamed gut.
      
 0.770
rhuM
Putative cytoplasmic protein; Pathogenicity island encoded protein: SPI3; RhuM (gi|4324608).
   
  
 0.753
sugR
ATP binding protein; Putative cytoplasmic protein; Pathogenicity island encoded protein: SPI3; putative ATP binding protein SugR (gi|4324607).
      
 0.723
fidL
Putative inner membrane protein; Pathogenicity island encoded protein: SPI3; FidL (gi|4324611).
   
  
 0.709
STM4258
Putative methyl-accepting chemotaxis protein; Hypothetical protein spi4_A (gi|7467268).
      
 0.643
stjC
Putative fimbrial chaparone protein; Similar to E. coli putative chaperone (AAC76247.1); Blastp hit to AAC76247.1 (224 aa), 49% identity in aa 1 - 223.
   
  
 0.643
iacP
Putative acyl carrier protein; Acyl carrier protein.
      
 0.579
stjB
Similar to E. coli putative outer membrane protein (AAC76248.1); Blastp hit to AAC76248.1 (793 aa), 40% identity in aa 29 - 793.
      
 0.579
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (42%) [HD]