Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
slsAPutative inner membrane protein; Pathogenicity island encoded protein: SPI3; SlsA (gi|4324613). (226 aa)    
Predicted Functional Partners:
STM3784
Putative phosphotransferase system mannitol/fructose-specific IIA domain containing protein; Similar to E. coli galactitol-specific enzyme IIA of phosphotransferase system (AAC75155.1); Blastp hit to AAC75155.1 (150 aa), 23% identity in aa 5 - 143.
   
  
 0.820
fidL
Putative inner membrane protein; Pathogenicity island encoded protein: SPI3; FidL (gi|4324611).
      
 0.726
STM1472
Putative periplasmic protein.
 
     0.723
STM0307
Homology to Shigella VirG protein.
   
  
 0.712
mgtB
Mg2+ transport protein; Mediates magnesium influx to the cytosol. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
  
  
 0.708
rhuM
Putative cytoplasmic protein; Pathogenicity island encoded protein: SPI3; RhuM (gi|4324608).
      
 0.679
STM0305
Putative cytoplasmic protein.
      
 0.677
mgtC
Mg2+ transport protein; Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase. Belongs to the MgtC/SapB family.
   
  
 0.674
sugR
ATP binding protein; Putative cytoplasmic protein; Pathogenicity island encoded protein: SPI3; putative ATP binding protein SugR (gi|4324607).
      
 0.646
marT
Pathogenicity island encoded protein: SPI3; putative transcriptional regulator MarT (gi|4324612).
   
  
 0.646
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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