Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
STM3770Putative phosphotransferase system enzyme IIC; Similar to E. coli PTS system N-acetylgalactosamine-specific IIC component 1 (AAC76173.1); Blastp hit to AAC76173.1 (267 aa), 31% identity in aa 19 - 232. (249 aa)    
Predicted Functional Partners:
STM3769
Putative phosphotransferase system enzyme II; Similar to E. coli PTS enzyme IID, mannose-specific (AAC74889.1); Blastp hit to AAC74889.1 (286 aa), 39% identity in aa 16 - 286.
 0.999
STM3771
Putative phosphotransferase system enzyme IIB; Similar to E. coli PTS enzyme IIAB, mannose-specific (AAC74887.1); Blastp hit to AAC74887.1 (323 aa), 29% identity in aa 164 - 320.
 
 0.995
manZ
Mannose-specific enzyme IID; Sugar Specific PTS family; similar to E. coli PTS enzyme IID, mannose-specific (AAC74889.1); Blastp hit to AAC74889.1 (286 aa), 92% identity in aa 1 - 285.
 
 0.991
STM3768
Putative selenocysteine synthase (L-seryl-tRNA(Ser) selenium transferase).
 
 
  0.991
STM3772
Putative phosphotransferase system enzyme IIA.
 
 0.991
STM4538
Putative PTS permease; Similar to E. coli PTS enzyme IID, mannose-specific (AAC74889.1); Blastp hit to AAC74889.1 (286 aa), 41% identity in aa 6 - 283.
 
 0.990
STM0574
Putative transport protein, PTS system; Similar to E. coli PTS enzyme IID, mannose-specific (AAC74889.1); Blastp hit to AAC74889.1 (286 aa), 37% identity in aa 4 - 284.
 
 0.986
STM3767
Putative cytoplasmic protein.
 
    0.935
manX
Mannose-specific enzyme IIAB; Sugar Specific PTS family; similar to E. coli PTS enzyme IIAB, mannose-specific (AAC74887.1); Blastp hit to AAC74887.1 (323 aa), 95% identity in aa 1 - 323.
 
 
 0.932
ptsH
Phosphohistidinoprotein-hexose phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
    
  0.902
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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