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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM3772Putative phosphotransferase system enzyme IIA. (141 aa)    
Predicted Functional Partners:
STM3771
Putative phosphotransferase system enzyme IIB; Similar to E. coli PTS enzyme IIAB, mannose-specific (AAC74887.1); Blastp hit to AAC74887.1 (323 aa), 29% identity in aa 164 - 320.
 
 
 0.997
STM3769
Putative phosphotransferase system enzyme II; Similar to E. coli PTS enzyme IID, mannose-specific (AAC74889.1); Blastp hit to AAC74889.1 (286 aa), 39% identity in aa 16 - 286.
 
 0.994
STM3770
Putative phosphotransferase system enzyme IIC; Similar to E. coli PTS system N-acetylgalactosamine-specific IIC component 1 (AAC76173.1); Blastp hit to AAC76173.1 (267 aa), 31% identity in aa 19 - 232.
 
 0.994
STM3773
Putative NtrC family transcriptional regulator; ATPase domain; similar to E. coli psp operon transcriptional activator (AAC74385.1); Blastp hit to AAC74385.1 (330 aa), 33% identity in aa 12 - 239.
 
  
 0.988
STM4535
Putative PTS permease; Similar to E. coli PTS enzyme IIAB, mannose-specific (AAC74887.1); Blastp hit to AAC74887.1 (323 aa), 22% identity in aa 6 - 127.
  
  
 0.966
STM3768
Putative selenocysteine synthase (L-seryl-tRNA(Ser) selenium transferase).
 
 
  0.963
STM0571
Putative inner membrane protein; Unknown (gi|2896134).
 
  
 0.947
STM4534
Putative NtrC family transcriptional regulator, ATPase domain protein; Similar to E. coli psp operon transcriptional activator (AAC74385.1); Blastp hit to AAC74385.1 (330 aa), 38% identity in aa 13 - 242.
 
   
 0.946
STM3256
Putative phosphotransferase system mannitol/fructose-specific IIA domain protein; Similar to E. coli PTS system, fructose-specific IIA/fpr component (AAC75230.1); Blastp hit to AAC75230.1 (376 aa), 52% identity in aa 3 - 141, 41% identity in aa 197 - 374.
   
 0.925
ptsH
Phosphohistidinoprotein-hexose phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
   
 0.919
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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