Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yicSPutative inner membrane protein. (97 aa)    
Predicted Functional Partners:
yaiY
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC73482.1); Blastp hit to AAC73482.1 (102 aa), 86% identity in aa 1 - 102.
      
 0.851
STM3021
Putative inner membrane protein.
      
 0.790
yebF
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74917.1); Blastp hit to AAC74917.1 (122 aa), 76% identity in aa 5 - 122.
      
 0.720
yicM
Putative MFS family tranport protein; Involved in the efflux of purine ribonucleosides, such as guanosine, adenosine and especially inosine. Involved in the resistance to 6-mercaptopurine; Belongs to the major facilitator superfamily. DHA1 family. NepI (TC 2.A.1.2.26) subfamily.
      
 0.714
ygdI
Putative lipoprotein; Similar to E. coli orf, hypothetical protein (AAC75851.1); Blastp hit to AAC75851.1 (76 aa), 93% identity in aa 2 - 75.
   
  
 0.673
cca
tRNA nucleotidyl transferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
      
 0.649
yciC
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74337.1); Blastp hit to AAC74337.1 (247 aa), 87% identity in aa 1 - 247.
      
 0.648
yjcH
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77038.1); Blastp hit to AAC77038.1 (104 aa), 89% identity in aa 1 - 102.
      
 0.645
nuoB
NADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
      
 0.540
STM3775
Putative glycosyl hydrolase family; Similar to E. coli 6-phospho-beta-glucosidase; cryptic (AAC75758.1); Blastp hit to AAC75758.1 (474 aa), 34% identity in aa 4 - 472; Belongs to the glycosyl hydrolase 1 family.
  
    0.530
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.