STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM3780Putative fructose-bisphosphate aldolase class-II; Similar to E. coli tagatose-bisphosphate aldolase 2 (AAC76171.1); Blastp hit to AAC76171.1 (286 aa), 36% identity in aa 1 - 277. (286 aa)    
Predicted Functional Partners:
STM3781
Putative sugar (pentulose and hexulose) kinase; Similar to E. coli L-fuculokinase (AAC75845.1); Blastp hit to AAC75845.1 (482 aa), 24% identity in aa 17 - 444.
  
  
 0.957
STM3782
Similar to E. coli PTS system galactitol-specific enzyme IIC (AAC75153.1); Blastp hit to AAC75153.1 (451 aa), 40% identity in aa 5 - 432.
  
    0.930
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.896
ygbL
Similar to E. coli putative epimerase/aldolase (AAC75780.1); Blastp hit to AAC75780.1 (212 aa), 85% identity in aa 1 - 211.
 
   
 0.878
ygbJ
Similar to E. coli putative dehydrogenase (AAC75778.1); Blastp hit to AAC75778.1 (302 aa), 82% identity in aa 1 - 299.
 
  
 0.868
gapA
Glyceraldehyde-3-phosphate dehydrogenase A; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
  
 0.859
STM3779
Putative phosphotransferase system; HPr-related protein; similar to E. coli PTS system protein HPr (AAC75468.1); Blastp hit to AAC75468.1 (85 aa), 28% identity in aa 1 - 83.
  
  
 0.848
pfkA
6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
 
 
 0.789
glpX
Similar to E. coli unknown function in glycerol metabolism (AAC76907.1); Blastp hit to AAC76907.1 (336 aa), 94% identity in aa 1 - 336.
  
 
 0.746
pgi
Similar to E. coli glucosephosphate isomerase (AAC76995.1); Blastp hit to AAC76995.1 (549 aa), 95% identity in aa 1 - 548.
  
 
 0.733
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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