STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yicNPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76686.1); Blastp hit to AAC76686.1 (159 aa), 82% identity in aa 10 - 159. (150 aa)    
Predicted Functional Partners:
glgS
rpoS dependent glycogen biosynthesis protein; Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.
      
 0.857
hflC
Component of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could regulate a protease.
      
 0.724
amiC
Similar to E. coli putative amidase (AAC75856.1); Blastp hit to AAC75856.1 (447 aa), 94% identity in aa 31 - 446.
   
  
 0.709
yicM
Putative MFS family tranport protein; Involved in the efflux of purine ribonucleosides, such as guanosine, adenosine and especially inosine. Involved in the resistance to 6-mercaptopurine; Belongs to the major facilitator superfamily. DHA1 family. NepI (TC 2.A.1.2.26) subfamily.
      0.706
uhpT
MFS family hexose phosphate transport protein; Mediates the exchange of external hexose 6-phosphate and internal inorganic phosphate.
     
 0.500
STM3785
Putative gntR family regulatory protein; Similar to E. coli transcriptional regulator of succinylCoA synthetase operon (AAC73824.1); Blastp hit to AAC73824.1 (240 aa), 31% identity in aa 3 - 216.
       0.416
STM3783
Putative periplasmic protein; Similar to E. coli galactitol-specific enzyme IIB of phosphotransferase system (AAC75154.1); Blastp hit to AAC75154.1 (94 aa), 37% identity in aa 1 - 94.
       0.413
STM3784
Putative phosphotransferase system mannitol/fructose-specific IIA domain containing protein; Similar to E. coli galactitol-specific enzyme IIA of phosphotransferase system (AAC75155.1); Blastp hit to AAC75155.1 (150 aa), 23% identity in aa 5 - 143.
       0.413
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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