Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dsdCLysR family transcriptional activator; Similar to E. coli D-serine dehydratase (deaminase) transcriptional activator (AAC75423.1); Blastp hit to AAC75423.1 (311 aa), 90% identity in aa 1 - 307; Belongs to the LysR transcriptional regulatory family. (307 aa)    
Predicted Functional Partners:
STM2361
Putative regulatory protein; Similar to E. coli response regulator of ato, ornithine decarboxylase antizyme (sensor ATOS) (AAC75280.1); Blastp hit to AAC75280.1 (461 aa), 39% identity in aa 122 - 456.
   
  
 0.953
cysB
Transcriptional regulator for cysteine regulon; This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription.
  
   
 0.811
xapR
Regulator for XapA; LysR family; similar to E. coli regulator for xapA (AAC75458.1); Blastp hit to AAC75458.1 (294 aa), 80% identity in aa 1 - 293; Belongs to the LysR transcriptional regulatory family.
  
     0.726
tdcA
LysR family; similar to E. coli transcriptional activator of tdc operon (AAC76153.1); Blastp hit to AAC76153.1 (312 aa), 89% identity in aa 1 - 311; Belongs to the LysR transcriptional regulatory family.
  
    0.716
STM3834
Similar to E. coli putative transcriptional regulator LYSR-type (AAC73855.1); Blastp hit to AAC73855.1 (338 aa), 27% identity in aa 22 - 318; Belongs to the LysR transcriptional regulatory family.
  
    0.713
sinR
Transcriptional regulator; Probable regulatory protein. Its target is not known.
  
     0.700
STM0763
Transcriptional regulator, lysR family; Similar to E. coli cyn operon positive regulator (AAC73441.1); Blastp hit to AAC73441.1 (299 aa), 25% identity in aa 16 - 288; Belongs to the LysR transcriptional regulatory family.
  
   
 0.698
STM2180
Similar to E. coli putative transcriptional regulator LYSR-type (AAC74504.1); Blastp hit to AAC74504.1 (354 aa), 28% identity in aa 54 - 336; Belongs to the LysR transcriptional regulatory family.
  
     0.683
ynfL
Similar to E. coli putative transcriptional regulator LYSR-type (AAC74667.1); Blastp hit to AAC74667.1 (297 aa), 83% identity in aa 1 - 297; Belongs to the LysR transcriptional regulatory family.
  
     0.658
dsdA
Similar to E. coli D-serine dehydratase (deaminase) (AAC75425.1); Blastp hit to AAC75425.1 (442 aa), 89% identity in aa 1 - 442.
 
  
 0.657
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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