Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
yidESimilar to E. coli putative transport protein (AAC76708.1); Blastp hit to AAC76708.1 (561 aa), 88% identity in aa 9 - 561. (553 aa)    
Predicted Functional Partners:
yggA
Putative LYSE family amino acid transport protein; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine (By similarity); Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
   
  
 0.562
ibpB
Small heat shock protein; Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
       0.471
dcuB
Dcu family anaerobic C4-dicarboxylate transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
  
    0.470
STM3599
Putative inner membrane protein; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
  
    0.452
dcuA
Dcu family anaerobic dicarboxylate transport protein; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
  
  
 0.442
STM4448
Putative phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
   
  
 0.424
yjjB
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77319.1); Blastp hit to AAC77319.1 (108 aa), 89% identity in aa 1 - 108.
 
  
 0.408
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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