Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yidQPutative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC76711.1); Blastp hit to AAC76711.1 (135 aa), 82% identity in aa 25 - 133. (111 aa)    
Predicted Functional Partners:
yieE
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76735.1); Blastp hit to AAC76735.1 (253 aa), 77% identity in aa 5 - 253.
      
 0.720
ibpA
Small heat shock protein; Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
     
 0.669
ynfK
Putative dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family.
      
 0.513
yceP
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74144.1); Blastp hit to AAC74144.1 (84 aa), 94% identity in aa 1 - 84.
      
 0.512
yghA
Similar to E. coli putative oxidoreductase (AAC76039.1); Blastp hit to AAC76039.1 (294 aa), 93% identity in aa 1 - 294.
   
  
 0.461
sfsA
Regulator for maltose metabolism; Binds to DNA non-specifically. Could be a regulatory factor involved in maltose metabolism.
      
 0.450
ibpB
Small heat shock protein; Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
  
  
 0.446
dedD
Putative lipoprotein; Non-essential cell division protein that could be required for efficient cell constriction.
      
 0.403
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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