STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccmE-2Periplasmic heme-dependent peroxidase; Cytochrome c-type biogenesis protein; similar to E. coli cytochrome c biogenesis, possible subunit of a heme lyase (AAC75257.1); Blastp hit to AAC75257.1 (159 aa), 82% identity in aa 1 - 159. (159 aa)    
Predicted Functional Partners:
ccmC-2
Cytochrome c-type biogenesis protein; similar to E. coli heme exporter protein C (AAC75259.1); Blastp hit to AAC75259.1 (245 aa), 86% identity in aa 1 - 245.
 
 0.998
ccmF-2
Similar to E. coli cytochrome c-type biogenesis protein (AAC75256.1); Blastp hit to AAC75256.1 (647 aa), 85% identity in aa 1 - 646.
 
 
 0.997
ccmH-2
Putative heme lyase subunit; Possible subunit of a heme lyase.
 
  
 0.994
ccmG-2
Heme lyase disulfide oxidoreductase; Cytochrome c-type biogenesis; similar to E. coli disulfide oxidoreductase (in biogenesis of cytochrome c? (AAC75255.1); Blastp hit to AAC75255.1 (185 aa), 87% identity in aa 1 - 185.
 
  
 0.992
ccmD-2
Cytochrome c-type biogenesis protein; similar to E. coli heme exporter protein C (AAC75258.1); Blastp hit to AAC75258.1 (69 aa), 77% identity in aa 1 - 69.
 
 
 0.992
ccmC
Heme exporter protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 0.991
ccmF
Similar to E. coli cytochrome c-type biogenesis protein (AAC75256.1); Blastp hit to AAC75256.1 (647 aa), 85% identity in aa 1 - 646.
 
 
 0.990
ccmB-2
Heme exporter protein; ABC superfamily (membrane); cytochrome c-type biogenesis protein; similar to E. coli heme exporter protein B, cytochrome c-type biogenesis protein (AAC75260.1); Blastp hit to AAC75260.1 (220 aa), 84% identity in aa 2 - 220.
 
 
 0.989
ccmH
Putative heme lyase subunit; Possible subunit of a heme lyase.
 
  
 0.977
ccmB
ABC superfamily (membrane) heme exporter protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
 
 0.970
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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