Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
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torATrimethylamine N-oxide reductase subunit; Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions. (850 aa)    
Predicted Functional Partners:
torD
Cytoplasmic chaperone which interacts with TorA; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; Belongs to the TorD/DmsD family. TorD subfamily.
 
 0.999
torC
Trimethylamine N-oxide reductase; Cytochrome c-type subunit; also has activity as negativer regulator of tor operon; similar to E. coli trimethylamine N-oxide reductase, cytochrome c-type subunit (AAC74081.1); Blastp hit to AAC74081.1 (390 aa), 90% identity in aa 1 - 388; Belongs to the TorC/TorY family.
 
 0.999
torT
TMAO reductase system periplasmic protein TorT; Regulates tor operon; similar to E. coli part of regulation of tor operon, periplasmic (AAC74079.1); Blastp hit to AAC74079.1 (342 aa), 65% identity in aa 1 - 342.
  
  
 0.887
torR
Two-component system, OmpR family, torCAD operon response regulator TorR; Regulates tor operon (TorR family); similar to E. coli response transcriptional regulator for torA (sensor TorS) (AAC74080.1); Blastp hit to AAC74080.1 (230 aa), 81% identity in aa 1 - 229.
 
  
 0.877
sufI
Suppressor of ftsI; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
      
 0.857
napC
Periplasmic nitrate reductase; Cytochrome c-type biogenesis protein; similar to E. coli cytochrome c-type protein (AAC75262.1); Blastp hit to AAC75262.1 (200 aa), 88% identity in aa 1 - 200.
 
 
 0.847
torS
Histidine kinase; Regulates tor operon; similar to E. coli sensor protein torS (regulator TorR) (AAC74078.1); Blastp hit to AAC74078.1 (904 aa), 62% identity in aa 1 - 896.
  
 
 0.846
pbpC
Transglycosylase of penicillin-binding protein 1c; Similar to E. coli putative peptidoglycan enzyme (AAC75572.1); Blastp hit to AAC75572.1 (770 aa), 82% identity in aa 7 - 767.
      
 0.769
hybB
Similar to E. coli probable cytochrome Ni/Fe component of hydrogenase-2 (AAC76031.1); Blastp hit to AAC76031.1 (392 aa), 96% identity in aa 1 - 392.
  
 0.759
tatC
Component of sec-independent protein export; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
   
 
 0.743
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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