Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dgoKSimilar to E. coli 2-oxo-3-deoxygalactonate kinase (AAC76716.1); Blastp hit to AAC76716.1 (292 aa), 81% identity in aa 1 - 292. (292 aa)    
Predicted Functional Partners:
dgoA
Galactonate dehydratase; Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy- D-galactonate.
 
 0.999
dgoR
Galactonate operon transcriptional repressor; GntR family; similar to E. coli regulator protein for dgo operon (AAC76718.1); Blastp hit to AAC76718.1 (128 aa), 94% identity in aa 1 - 112.
  
 0.995
dgoT
MFS family D-galactonate transport protein; Similar to E. coli D-galactonate transport (AAC76714.1); Blastp hit to AAC76714.1 (445 aa), 90% identity in aa 1 - 445.
 
  
 0.932
STM3134
Putative permease; Similar to E. coli transport of hexuronates (AAC76128.1); Blastp hit to AAC76128.1 (472 aa), 47% identity in aa 43 - 454.
  
  
 0.860
STM3169
Similar to E. coli putative solute-binding transport protein (AAC76603.1); Blastp hit to AAC76603.1 (328 aa), 28% identity in aa 7 - 320.
   
  
 0.650
yidR
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76712.1); Blastp hit to AAC76712.1 (416 aa), 79% identity in aa 13 - 416.
 
    0.622
yfhB
Putatative phosphoserine phosphatase; Similar to E. coli orf, hypothetical protein (AAC75613.1); Blastp hit to AAC75613.1 (190 aa), 91% identity in aa 1 - 190.
      
 0.579
yafB
2,5-diketo-D-gluconate reductase B; Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).
   
  
 0.551
yohK
Putative transmembrane protein; Similar to E. coli putative seritonin transporter (AAC75203.1); Blastp hit to AAC75203.1 (231 aa), 90% identity in aa 1 - 230.
      
 0.550
yidA
Putative hydrolase of the HAD superfamily; Similar to E. coli orf, hypothetical protein (AAC76720.1); Blastp hit to AAC76720.1 (270 aa), 93% identity in aa 1 - 270.
  
    0.533
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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