Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yieFPutative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC76736.1); Blastp hit to AAC76736.1 (188 aa), 92% identity in aa 1 - 187. (194 aa)    
Predicted Functional Partners:
yieE
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76735.1); Blastp hit to AAC76735.1 (253 aa), 77% identity in aa 5 - 253.
 
  
 0.991
mdaB
NADPH specific quinone oxidoreductase; Drug modulator; similar to E. coli modulator of drug activity B (AAC76064.1); Blastp hit to AAC76064.1 (193 aa), 92% identity in aa 1 - 192.
     
 0.767
yebC
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74934.1); Blastp hit to AAC74934.1 (246 aa), 98% identity in aa 1 - 246.
      
 0.722
ychH
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74289.1); Blastp hit to AAC74289.1 (92 aa), 91% identity in aa 1 - 92.
      
 0.719
yhbO
Putative intracellular proteinase; Similar to E. coli orf, hypothetical protein (AAC76187.1); Blastp hit to AAC76187.1 (186 aa), 94% identity in aa 15 - 186.
  
  
 0.688
yhcN
Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC76270.1); Blastp hit to AAC76270.1 (104 aa), 79% identity in aa 18 - 104.
      
 0.677
fhuE
Outer membrane receptor for Fe(III)-coprogen; Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid uptake; similar to E. coli outer membrane receptor for ferric iron uptake (AAC74186.1); Blastp hit to AAC74186.1 (729 aa), 81% identity in aa 5 - 729.
 
      0.645
mdaA
Oxygen-insensitive NADPH nitroreductase; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product.
      
 0.586
ybgR
Putative CDF family transport protein; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
     
 0.567
orn
Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
   
  
 0.559
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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