Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
yieGPutative xanthine/uracil permeases family; Similar to E. coli putative membrane / transport protein (AAC76737.1); Blastp hit to AAC76737.1 (445 aa), 96% identity in aa 1 - 445. (487 aa)    
Predicted Functional Partners:
yicE
Similar to E. coli putative transport protein (AAC76678.1); Blastp hit to AAC76678.1 (463 aa), 95% identity in aa 1 - 462.
 
  
 0.918
yieH
Similar to E. coli putative phosphatase (AAC76738.1); Blastp hit to AAC76738.1 (221 aa), 81% identity in aa 1 - 220.
  
    0.798
yihZ
D-Tyr-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.
   
  
 0.769
purG
Phosphoribosylformylglycinamidine synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.751
yjcD
Putative xanthine/uracil permease family; Similar to E. coli orf, hypothetical protein (AAC77034.1); Blastp hit to AAC77034.1 (449 aa), 97% identity in aa 1 - 449.
  
   
0.746
yhfC
Putative MFS family transport protein; Similar to E. coli putative transport (AAC76389.1); Blastp hit to AAC76389.1 (393 aa), 90% identity in aa 1 - 393.
  
  
 0.733
uraA
NCS2 family uracil transport protein; Similar to E. coli uracil transport (AAC75550.1); Blastp hit to AAC75550.1 (429 aa), 94% identity in aa 1 - 425.
 
  
 0.594
purD
GAR synthetase; phosphoribosylamine--glycine ligase. (SW:PUR2_SALTY); Belongs to the GARS family.
  
  
 0.563
purE
Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
    0.531
STM3631
Similar to E. coli putative permease (AAC75926.1); Blastp hit to AAC75926.1 (505 aa), 27% identity in aa 54 - 466.
 
  
 0.478
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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