close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pstBHigh-affinity phosphate transporter; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (257 aa)    
Predicted Functional Partners:
phoU
Regulatory gene for high affinity phosphate uptake; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.
  
 0.999
pstA
ABC superfamily (membrane); similar to E. coli high-affinity phosphate-specific transport system (AAC76749.1); Blastp hit to AAC76749.1 (296 aa), 95% identity in aa 1 - 296.
 
 0.999
pstC
High-affinity phosphate transporter; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 0.999
pstS
High-affinity phosphate transporter; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
 
 0.999
STM3528
Putative periplasmic phosphate-binding protein.
 
 
 0.973
ybbL
Putative ABC-type sugar/spermidine/putrescine transport system, ATPase component; Similar to E. coli putative ATP-binding component of a transport system (AAC73592.1); Blastp hit to AAC73592.1 (225 aa), 74% identity in aa 1 - 225.
 
    
0.906
cydD
Cytochrome-related transporter; Zn sensitive; ABC superfamily (atp&memb); similar to E. coli ATP-binding component of cytochrome-related transport, Zn sensitive (AAC73973.1); Blastp hit to AAC73973.1 (588 aa), 90% identity in aa 1 - 588.
 
     
0.900
STM2691
Putative ABC transporter transmembrane region; Similar to E. coli ATP-binding transport protein; multicopy suppressor of htrB (AAC74000.1); Blastp hit to AAC74000.1 (582 aa), 26% identity in aa 20 - 557.
     
0.900
sapD
ABC superfamily peptide transport protein; Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides. Belongs to the ABC transporter superfamily.
 
     
0.890
pitA
PiT family; similar to E. coli low-affinity phosphate transport (AAC76518.1); Blastp hit to AAC76518.1 (499 aa), 92% identity in aa 1 - 499.
     
 0.851
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (40%) [HD]