Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yieMPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76768.1); Blastp hit to AAC76768.1 (427 aa), 89% identity in aa 1 - 427. (474 aa)    
Predicted Functional Partners:
yieN
Putative regulator protein; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone; Belongs to the RavA family.
  
 0.998
ycbW
Putative cytoplasmic protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
  
     0.754
ycfP
Putative esterase; Similar to E. coli orf, hypothetical protein (AAC74192.1); Blastp hit to AAC74192.1 (199 aa), 94% identity in aa 20 - 199; Belongs to the UPF0227 family.
  
     0.707
yhhN
Putative inner membrane protein; Similar to E. coli putative enzyme (AAC76493.1); Blastp hit to AAC76493.1 (208 aa), 91% identity in aa 1 - 208.
  
     0.692
yajG
Similar to E. coli putative polymerase/proteinase (AAC73537.1); Blastp hit to AAC73537.1 (226 aa), 85% identity in aa 20 - 226.
  
     0.682
ilvM
Similar to E. coli acetolactate synthase II, valine insensitive, small subunit (AAC77489.1); Blastp hit to AAC77489.1 (87 aa), 93% identity in aa 2 - 87.
  
     0.674
yiiU
Putative cytoplasmic protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
     0.674
cyaA
Adenylate cyclase. (SW:CYAA_SALTY).
  
    0.655
cadA
Lysine decarboxylase, inducible. (SW:DCLY_SALTY); Belongs to the Orn/Lys/Arg decarboxylase class-I family.
      
 0.648
spy
Similar to E. coli periplasmic protein related to spheroblast formation (AAC74813.1); Blastp hit to AAC74813.1 (161 aa), 89% identity in aa 1 - 161.
  
   
 0.628
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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