Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rbsCD-ribose high-affinity transport protein (1st module, ATP-binding subunit); ABC superfamily (membrane); similar to E. coli D-ribose high-affinity transport system (AAC76773.1); Blastp hit to AAC76773.1 (321 aa), 96% identity in aa 1 - 321; Belongs to the binding-protein-dependent transport system permease family. (321 aa)    
Predicted Functional Partners:
rbsA
D-ribose high-affinity transport protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
 0.999
rbsB
D-ribose transport protein; Part of the ABC transporter complex RbsABC involved in ribose import. Binds ribose.
 0.999
rbsD
D-ribose high-affinity transport system; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
 
  
 0.992
mglA
Galactose (methyl-galactoside) transport protein; Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system (Probable).
 
 0.982
ego
Putative ABC-type sugar aldose transport system; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system (Probable).
 
 0.981
gltK
Glutamate/aspartate transporter; ABC superfamily (membrane); similar to E. coli glutamate/aspartate transport system permease (AAC73754.1); Blastp hit to AAC73754.1 (224 aa), 95% identity in aa 1 - 223.
      
 0.897
mglB
Galactose transport protein; This protein is involved in the active transport of galactose and glucose. It plays a role in the chemotaxis towards the two sugars by interacting with the trg chemoreceptor.
 
 
 0.897
yciB
Putative intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
      
 0.896
ptsG
Glucose-specific IIBC component of the Sugar Specific PTS family; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. Also functions as a chemoreceptor monitoring the environment for changes in sugar concentration. It can also phosphorylate mannose, methyl alpha-glucoside and 2-deoxy-glucose.
   
  
 0.834
yneA
Putative sugar transport protein; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (Probable); Belongs to the bacterial solute-binding protein 2 family.
 
 0.827
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (10%) [HD]