STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yifBPutative magnesium chelatase, subunit ChlI; Hypothetical 55.0 Kda protein in pssR-ilLl intergenic region. (SW:YIFB_SALTY); Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. (506 aa)    
Predicted Functional Partners:
ilvL
ilvGmedA operon leader peptide (attenuator peptide). (SW:LPID_ECOLI).
     
 0.950
smf
Putative protein involved in DNA uptake; Similar to E. coli orf, fragment 1 (AAC76311.1); Blastp hit to AAC76311.1 (253 aa), 66% identity in aa 1 - 248.
 
 0.927
yhgH
Putative amidophosphoribosyltransferase; Could be involved in gluconate metabolism.
 
  
 0.860
hrpB
Similar to E. coli helicase, ATP-dependent (AAC73259.1); Blastp hit to AAC73259.1 (824 aa), 84% identity in aa 1 - 824.
   
  
 0.805
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
     0.775
citT
DASS family, citrate:succinate transport (antiport) protein; Similar to E. coli putative a membrane protein (AAC73713.1); Blastp hit to AAC73713.1 (487 aa), 94% identity in aa 1 - 487.
  
  
 0.773
yraN
Putative endonuclease; Similar to E. coli orf, hypothetical protein (AAC76182.1); Blastp hit to AAC76182.1 (131 aa), 83% identity in aa 1 - 131; Belongs to the UPF0102 family.
 
  
 0.716
gntT
GntP family; similar to E. coli high-affinity transport of gluconate / gluconate permease (AAC76440.1); Blastp hit to AAC76440.1 (437 aa), 96% identity in aa 1 - 437.
      
 0.716
ruvC
Holliday junction nuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
   
 0.627
ycaI
Putative recombination protein; Similar to E. coli orf, hypothetical protein (AAC73999.1); Blastp hit to AAC73999.1 (780 aa), 70% identity in aa 27 - 780.
 
  
 0.576
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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