| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dapF | hemX | STM3947 | STM3936 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Similar to E. coli uroporphyrinogen III methylase (AAC76806.1); Blastp hit to AAC76806.1 (393 aa), 87% identity in aa 1 - 393. | 0.452 |
| dapF | uvrD | STM3947 | STM3951 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | DNA-dependent ATPase I and helicase II; Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Belongs to the helicase family. UvrD subfamily. | 0.747 |
| dapF | xerC | STM3947 | STM3949 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Putative site-specific integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC speci [...] | 0.940 |
| dapF | yifL | STM3947 | STM3946 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Putative outer membrane lipoprotein. | 0.803 |
| dapF | yigA | STM3947 | STM3948 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Putative cytoplasmic protein; Hypothetical protein in dapF-xerC intergenic region. (SW:YIGA_SALTY). | 0.969 |
| dapF | yigB | STM3947 | STM3950 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Putative hydrolase of the HAD superfamily; Similar to E. coli putative phosphatase (AAC76815.1); Blastp hit to AAC76815.1 (238 aa), 87% identity in aa 1 - 238. | 0.826 |
| dapF | yigP | STM3947 | STM3971 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Putative inner membrane protein; Required for ubiquinone (coenzyme Q) biosynthesis under aerobic conditions. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex (By similarity). May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates (By similarity). Required for intracellular proliferation in macrophages. Belongs to the UbiJ family. | 0.420 |
| hemX | dapF | STM3936 | STM3947 | Similar to E. coli uroporphyrinogen III methylase (AAC76806.1); Blastp hit to AAC76806.1 (393 aa), 87% identity in aa 1 - 393. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.452 |
| hemX | yigA | STM3936 | STM3948 | Similar to E. coli uroporphyrinogen III methylase (AAC76806.1); Blastp hit to AAC76806.1 (393 aa), 87% identity in aa 1 - 393. | Putative cytoplasmic protein; Hypothetical protein in dapF-xerC intergenic region. (SW:YIGA_SALTY). | 0.741 |
| hemX | yigP | STM3936 | STM3971 | Similar to E. coli uroporphyrinogen III methylase (AAC76806.1); Blastp hit to AAC76806.1 (393 aa), 87% identity in aa 1 - 393. | Putative inner membrane protein; Required for ubiquinone (coenzyme Q) biosynthesis under aerobic conditions. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex (By similarity). May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates (By similarity). Required for intracellular proliferation in macrophages. Belongs to the UbiJ family. | 0.459 |
| uvrD | dapF | STM3951 | STM3947 | DNA-dependent ATPase I and helicase II; Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Belongs to the helicase family. UvrD subfamily. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.747 |
| uvrD | xerC | STM3951 | STM3949 | DNA-dependent ATPase I and helicase II; Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Belongs to the helicase family. UvrD subfamily. | Putative site-specific integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC speci [...] | 0.840 |
| uvrD | yifL | STM3951 | STM3946 | DNA-dependent ATPase I and helicase II; Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Belongs to the helicase family. UvrD subfamily. | Putative outer membrane lipoprotein. | 0.643 |
| uvrD | yigA | STM3951 | STM3948 | DNA-dependent ATPase I and helicase II; Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Belongs to the helicase family. UvrD subfamily. | Putative cytoplasmic protein; Hypothetical protein in dapF-xerC intergenic region. (SW:YIGA_SALTY). | 0.720 |
| uvrD | yigB | STM3951 | STM3950 | DNA-dependent ATPase I and helicase II; Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Belongs to the helicase family. UvrD subfamily. | Putative hydrolase of the HAD superfamily; Similar to E. coli putative phosphatase (AAC76815.1); Blastp hit to AAC76815.1 (238 aa), 87% identity in aa 1 - 238. | 0.747 |
| xerC | dapF | STM3949 | STM3947 | Putative site-specific integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC speci [...] | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.940 |
| xerC | uvrD | STM3949 | STM3951 | Putative site-specific integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC speci [...] | DNA-dependent ATPase I and helicase II; Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Belongs to the helicase family. UvrD subfamily. | 0.840 |
| xerC | yifL | STM3949 | STM3946 | Putative site-specific integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC speci [...] | Putative outer membrane lipoprotein. | 0.765 |
| xerC | yigA | STM3949 | STM3948 | Putative site-specific integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC speci [...] | Putative cytoplasmic protein; Hypothetical protein in dapF-xerC intergenic region. (SW:YIGA_SALTY). | 0.922 |
| xerC | yigB | STM3949 | STM3950 | Putative site-specific integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC speci [...] | Putative hydrolase of the HAD superfamily; Similar to E. coli putative phosphatase (AAC76815.1); Blastp hit to AAC76815.1 (238 aa), 87% identity in aa 1 - 238. | 0.843 |
