Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rhtCRhtB family threonine efflux protein; Conducts the efflux of threonine; Belongs to the Rht family. (206 aa)    
Predicted Functional Partners:
alaE
Putative inner membrane protein; Exports L-alanine; Belongs to the AlaE exporter family.
      
 0.695
recQ
ATP-dependent DNA helicase; Involved in the RecF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
    0.658
rthB
Homoserine/homoserine lactone efflux protein; Conducts the efflux of homoserine and homoserine lactone. Belongs to the Rht family.
  
  
0.641
yabF
Putative NAD(P)H oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
      
 0.634
ybiF
Putative permease; Involved in the efflux of threonine and homoserine. Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family.
  
  
 0.546
pldA
Outer membrane phospholipase A; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities; Belongs to the phospholipase A1 family.
  
  
 0.540
rarD
Chloramphenicol resistance; Similar to E. coli orf, hypothetical protein (AAC76822.1); Blastp hit to AAC76822.1 (300 aa), 83% identity in aa 8 - 297.
 
  
 0.484
yraL
Putative methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
      
 0.450
yigI
Putative PaaI protein; Possibly involved in aromatic compounds catabolism; hypothetical protein in rarD-pldA intergenic region. (SW:YIGI_SALTY).
 
  
 0.436
fadH
2,4-dieonyl-coa reductase; Similar to E. coli putative NADPH dehydrogenase (AAC76116.1); Blastp hit to AAC76116.1 (672 aa), 85% identity in aa 1 - 672.
  
  
 0.412
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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