Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yigLPutative hydrolase of the HAD superfamily; Similar to E. coli orf, hypothetical protein (AAC76829.1); Blastp hit to AAC76829.1 (171 aa), 85% identity in aa 1 - 167. (266 aa)    
Predicted Functional Partners:
pldB
Similar to E. coli lysophospholipase L(2) (AAC76828.1); Blastp hit to AAC76828.1 (340 aa), 81% identity in aa 1 - 336.
 
  
 0.994
yigM
Putative transport protein; Uptake of biotin; Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family.
 
  
 0.965
yniC
Similar to E. coli putative phosphatase (AAC74797.1); Blastp hit to AAC74797.1 (222 aa), 90% identity in aa 1 - 222.
  
  
 0.895
rne
RNase E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.
   
  
 0.857
ptsG
Glucose-specific IIBC component of the Sugar Specific PTS family; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. Also functions as a chemoreceptor monitoring the environment for changes in sugar concentration. It can also phosphorylate mannose, methyl alpha-glucoside and 2-deoxy-glucose.
 
   
 0.805
yabN
Putative periplasmic binding protein of transport system; Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.
      
 0.767
manX
Mannose-specific enzyme IIAB; Sugar Specific PTS family; similar to E. coli PTS enzyme IIAB, mannose-specific (AAC74887.1); Blastp hit to AAC74887.1 (323 aa), 95% identity in aa 1 - 323.
     
 0.728
yeiB
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75213.1); Blastp hit to AAC75213.1 (385 aa), 84% identity in aa 1 - 377.
      
 0.725
STM0867
Putative hydrolase; Similar to E. coli orf, hypothetical protein (AAC73931.1); Blastp hit to AAC73931.1 (262 aa), 82% identity in aa 1 - 261.
  
     0.709
yedP
Putative hydrolase of the HAD superfamily; Similar to E. coli orf, hypothetical protein (AAC75021.1); Blastp hit to AAC75021.1 (271 aa), 75% identity in aa 1 - 269.
      
 0.675
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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