node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
amiC | glpG | STM2991 | STM3524 | Similar to E. coli putative amidase (AAC75856.1); Blastp hit to AAC75856.1 (447 aa), 94% identity in aa 31 - 446. | Protein of glp regulon; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.506 |
amiC | sufI | STM2991 | STM3172 | Similar to E. coli putative amidase (AAC75856.1); Blastp hit to AAC75856.1 (447 aa), 94% identity in aa 31 - 446. | Suppressor of ftsI; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress. | 0.901 |
amiC | tatA | STM2991 | STM3973 | Similar to E. coli putative amidase (AAC75856.1); Blastp hit to AAC75856.1 (447 aa), 94% identity in aa 31 - 446. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.695 |
amiC | tatB | STM2991 | STM3974 | Similar to E. coli putative amidase (AAC75856.1); Blastp hit to AAC75856.1 (447 aa), 94% identity in aa 31 - 446. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.707 |
amiC | tatC | STM2991 | STM3975 | Similar to E. coli putative amidase (AAC75856.1); Blastp hit to AAC75856.1 (447 aa), 94% identity in aa 31 - 446. | Component of sec-independent protein export; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.851 |
amiC | yigW | STM2991 | STM3976 | Similar to E. coli putative amidase (AAC75856.1); Blastp hit to AAC75856.1 (447 aa), 94% identity in aa 31 - 446. | Putative hydrolase of PHP superfamily; 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair. Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily. | 0.431 |
flk | tatA | STM2371 | STM3973 | Cell division protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion (T3S) system. Plays a role in hindering to flip the flagellar T3S specificity switch from the rod and hook-type substrates to filament-type substrates prior to hook-basal body (HBB) completion possibly by preventing interaction of FliK with FlhB. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.672 |
flk | tatB | STM2371 | STM3974 | Cell division protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion (T3S) system. Plays a role in hindering to flip the flagellar T3S specificity switch from the rod and hook-type substrates to filament-type substrates prior to hook-basal body (HBB) completion possibly by preventing interaction of FliK with FlhB. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.677 |
flk | tatC | STM2371 | STM3975 | Cell division protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion (T3S) system. Plays a role in hindering to flip the flagellar T3S specificity switch from the rod and hook-type substrates to filament-type substrates prior to hook-basal body (HBB) completion possibly by preventing interaction of FliK with FlhB. | Component of sec-independent protein export; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.662 |
glpG | amiC | STM3524 | STM2991 | Protein of glp regulon; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | Similar to E. coli putative amidase (AAC75856.1); Blastp hit to AAC75856.1 (447 aa), 94% identity in aa 31 - 446. | 0.506 |
glpG | tatA | STM3524 | STM3973 | Protein of glp regulon; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.636 |
glpG | tatB | STM3524 | STM3974 | Protein of glp regulon; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.559 |
guaA | tatA | STM2510 | STM3973 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.914 |
guaA | tatB | STM2510 | STM3974 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.914 |
guaA | tatC | STM2510 | STM3975 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Component of sec-independent protein export; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.403 |
secA | secG | STM0136 | STM3293 | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | Preprotein translocase IISP family protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.999 |
secA | tatA | STM0136 | STM3973 | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.709 |
secA | tatB | STM0136 | STM3974 | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.701 |
secA | tatC | STM0136 | STM3975 | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | Component of sec-independent protein export; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.785 |
secG | secA | STM3293 | STM0136 | Preprotein translocase IISP family protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.999 |