Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yihIPutative cytoplasmic protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. (171 aa)    
Predicted Functional Partners:
yifE
Putative LysR type transcriptional regulator with pssR; Similar to E. coli orf, hypothetical protein (AAC77485.1); Blastp hit to AAC77485.1 (112 aa), 95% identity in aa 1 - 112; Belongs to the UPF0438 family.
  
  
 0.884
yceD
Putative metal-binding protein; Plays a role in synthesis, processing and/or stability of 23S rRNA; Belongs to the DUF177 domain family.
  
   
 0.869
syd
Interacts with secY; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.
  
   
 0.864
yibL
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76626.1); Blastp hit to AAC76626.1 (120 aa), 90% identity in aa 1 - 120.
   
  
 0.859
ybcJ
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73630.1); Blastp hit to AAC73630.1 (77 aa), 92% identity in aa 8 - 77.
      
 0.856
yigA
Putative cytoplasmic protein; Hypothetical protein in dapF-xerC intergenic region. (SW:YIGA_SALTY).
  
  
 0.836
proQ
Activator of proP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family.
  
  
 0.833
hemN
O2-independent coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
      0.825
yfbV
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75355.1); Blastp hit to AAC75355.1 (151 aa), 95% identity in aa 1 - 151.
  
   
 0.823
ygiF
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76090.1); Blastp hit to AAC76090.1 (433 aa), 85% identity in aa 1 - 433.
  
   
 0.815
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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