STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
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[Homology]
Score
STM4012Putative coproporphyrinogen III oxidase and related FeS oxidoreductase; Similar to E. coli O2-independent coproporphyrinogen III oxidase (AAC76864.1); Blastp hit to AAC76864.1 (459 aa), 28% identity in aa 14 - 248, 25% identity in aa 319 - 379. (413 aa)    
Predicted Functional Partners:
STM4011
Putative inner membrane protein.
 
  
 0.984
STM4015
Putative cytoplasmic protein.
 
    0.976
STM4013
Putative membrane-associated metal-dependent hydrolase.
 
    0.973
STM4014
Putative periplasmic protein.
 
    0.970
hemF
Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
    
 0.925
hemN
O2-independent coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
  
  
 
0.920
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.920
hemG
Protoporphyrin oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX using menaquinone as electron acceptor.
  
 
  0.905
ftn
Cytoplasmic ferritin; Iron-storage protein.
      
 0.851
STM4010
Similar to E. coli putative phosphatase (AAC73853.1); Blastp hit to AAC73853.1 (272 aa), 44% identity in aa 147 - 267, 30% identity in aa 1 - 169.
  
    0.833
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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