close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM4013Putative membrane-associated metal-dependent hydrolase. (291 aa)    
Predicted Functional Partners:
STM4011
Putative inner membrane protein.
 
    0.985
STM4012
Putative coproporphyrinogen III oxidase and related FeS oxidoreductase; Similar to E. coli O2-independent coproporphyrinogen III oxidase (AAC76864.1); Blastp hit to AAC76864.1 (459 aa), 28% identity in aa 14 - 248, 25% identity in aa 319 - 379.
 
    0.971
STM4015
Putative cytoplasmic protein.
 
    0.971
STM4014
Putative periplasmic protein.
 
    0.969
STM4010
Similar to E. coli putative phosphatase (AAC73853.1); Blastp hit to AAC73853.1 (272 aa), 44% identity in aa 147 - 267, 30% identity in aa 1 - 169.
  
    0.849
envE
Putative envelope protein; Probable lipoprotein ENVE precursor. (SW:ENVE_SALTY).
 
     0.668
yeaS
Putative transport protein; Exporter of leucine; Belongs to the Rht family.
  
     0.580
STM2599
Gifsy-1 prophage protein; Similar to E. coli putative virulence protein (AAC74514.1); Blastp hit to AAC74514.1 (402 aa), 36% identity in aa 1 - 384.
  
     0.580
ygjQ
Putative integral membrane protein; Similar to E. coli orf, hypothetical protein (AAC76121.1); Blastp hit to AAC76121.1 (230 aa), 73% identity in aa 1 - 230.
  
     0.542
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
   
    0.539
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (56%) [HD]