Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yihTPutative aldolase; Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA). Belongs to the aldolase LacD family. (292 aa)    
Predicted Functional Partners:
yihU
Putative oxidoreductase; Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1- sulfonate (DHPS); Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily.
 
 
 0.992
yihR
Similar to E. coli putative aldose-1-epimerase (AAC76876.1); Blastp hit to AAC76876.1 (308 aa), 54% identity in aa 9 - 303.
 
  
 0.988
yihV
Putative sugar kinase; Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6-deoxy-6- sulfo-D-fructose 1-phosphate (SFP); Belongs to the carbohydrate kinase PfkB family.
 
 
 0.987
yihS
Putative isomerase; Catalyzes the isomerization of sulfoquinovose (SQ) to 6- deoxy-6-sulfo-D-fructose (SF) (By similarity). In vitro, can also catalyze the interconversion of mannose, fructose and glucose, but has extremely low activity with glucose. Belongs to the N-acylglucosamine 2-epimerase family.
  
  
 0.984
yihQ
Similar to E. coli putative glycosidase (AAC76875.1); Blastp hit to AAC76875.1 (678 aa), 88% identity in aa 10 - 678; Belongs to the glycosyl hydrolase 31 family.
 
  
 0.975
yihW
Putative glycerol-3-phosphate regulon repressor; DeoR family; similar to E. coli putative DEOR-type transcriptional regulator (AAD13446.1); Blastp hit to AAD13446.1 (269 aa), 89% identity in aa 9 - 263.
 
  
 0.903
yshA
Putative outer membrane protein; Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is unknown (By similarity); Belongs to the oligogalacturonate-specific porin KdgM (TC 1.B.35) family. OmpL subfamily.
  
  
 0.848
yihO
Putative GPH family transport protein; Could be involved in sulfoquinovose import; Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
  
  
 0.762
wcaC
Putative glycosyl transferase; In colanic acid gene cluster; similar to E. coli putative glycosyl transferase (AAC75118.1); Blastp hit to AAC75118.1 (405 aa), 80% identity in aa 1 - 405.
  
    0.749
fadH
2,4-dieonyl-coa reductase; Similar to E. coli putative NADPH dehydrogenase (AAC76116.1); Blastp hit to AAC76116.1 (672 aa), 85% identity in aa 1 - 672.
   
  
 0.721
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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