STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM4031Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76118.1); Blastp hit to AAC76118.1 (104 aa), 40% identity in aa 1 - 99. (103 aa)    
Predicted Functional Partners:
STM4030
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76117.1); Blastp hit to AAC76117.1 (138 aa), 45% identity in aa 19 - 138.
 
 
 0.995
vapC
Putative nucleic acid-binding protein; Toxic component of a type II toxin-antitoxin (TA) system. A site-specific tRNA-(fMet) endonuclease, it cleaves both charged and uncharged tRNA-(fMet) between positions 38 and 39 at the anticodon stem-loop boundary. Does not cleave tRNA(Met), tRNA(Arg2), tRNA(His), tRNA(Leu), tRNA(Phe) tRNA(Thr1), tRNA(Tyr) or tRNA(Val). Overexpression in E.coli inhibits translation, leads to loss of cell growth and degradation of tRNA(fMet), these effects are neutralized by expression of cognate antitoxin VapB. Expression also activates translation initiation at c [...]
  
     0.609
STM4032
Putative acetyl esterase; Similar to E. coli putative lipase (AAC73578.1); Blastp hit to AAC73578.1 (319 aa), 32% identity in aa 84 - 312.
  
    0.572
ybeV
Putative molecular chaperone, DnaJ family; Similar to E. coli orf, hypothetical protein (AAC73750.1); Blastp hit to AAC73750.1 (483 aa), 58% identity in aa 1 - 434.
  
    0.492
STM3198
Putative inner membrane protein; Similar to E. coli putative oxidoreductase (AAC76086.1); Blastp hit to AAC76086.1 (209 aa), 72% identity in aa 1 - 201.
  
     0.490
csgB
Minor curlin subunit precursor; Curlin is the structural subunit of the curli. Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers; Belongs to the CsgA/CsgB family.
  
     0.489
STM3516
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73329.1); Blastp hit to AAC73329.1 (92 aa), 78% identity in aa 1 - 91.
  
   
 0.483
STM4450
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74636.1); Blastp hit to AAC74636.1 (95 aa), 67% identity in aa 1 - 94.
  
   
 0.475
vapB
Putative cytoplasmic protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli neutralizes the effect of cognate toxin VapC.
  
     0.458
STM3517
Putative DNA-damage-inducibile protein; Resembles dinJ; similar to E. coli damage-inducible protein J (AAC73330.1); Blastp hit to AAC73330.1 (86 aa), 83% identity in aa 1 - 86.
  
  
 0.455
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.