Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fdhEPutative formate dehydrogenase formation protein; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (309 aa)    
Predicted Functional Partners:
fdoI
Similar to E. coli formate dehydrogenase, cytochrome B556 (FDO) subunit (AAD13454.1); Blastp hit to AAD13454.1 (211 aa), 96% identity in aa 1 - 211.
 
  
 0.996
fdoG
Similar to E. coli formate dehydrogenase-O, major subunit (AAD13456.1); Blastp hit to AAD13456.1 (1016 aa), 93% identity in aa 1 - 1016.
 
 0.990
fdnG
Putative molybdopterin oxidoreductases; Similar to E. coli formate dehydrogenase-N, nitrate-inducible, alpha subunit (AAD13438.1); Blastp hit to AAD13438.1 (1015 aa), 93% identity in aa 1 - 1015; contains selenocysteine tRNA suppressible codon.
 
 0.982
fdoH
Formate dehydrogenase-O, Fe-S subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
  
 0.980
fdhD
Putative formate dehydrogenase formation protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
  
 0.961
fdnI
Nitrate-inducible; similar to E. coli formate dehydrogenase-N, nitrate-inducible, cytochrome B556(Fdn) gamma subunit (AAD13440.1); Blastp hit to AAD13440.1 (217 aa), 98% identity in aa 1 - 217.
 
  
 0.926
selB
Similar to E. coli selenocysteinyl-tRNA-specific translation factor (AAC76614.1); Blastp hit to AAC76614.1 (614 aa), 85% identity in aa 1 - 614.
 
   
 0.877
fdnH
Formate dehydrogenase-N, Fe-S beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
  
 0.844
selD
Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP.
 
  
 0.838
selA
Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family.
 
  
 0.823
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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