STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rhaAL-rhamnose isomerase. (SW:RHAA_SALTY). (419 aa)    
Predicted Functional Partners:
yiiL
Putative cytoplasmic protein; Involved in the anomeric conversion of L-rhamnose.
 
 
 0.999
rhaB
Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family.
 
 0.999
rhaD
Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Belongs to the aldolase class II family. RhaD subfamily.
  
 0.998
rhaT
DMT Superfamily L-rhamnose:H+ symporter protein; Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system); Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
 
  
 0.947
fucI
L-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose.
  
  
 0.936
fucK
L-fuculokinase; Catalyzes the phosphorylation of L-fuculose. Belongs to the FGGY kinase family.
 
  
 0.926
rhaS
Positive regulator for rhaBAD operon; Activates expression of the rhaBAD and rhaT operons.
 
  
 0.909
rhaR
Positive regulator for rhaRS operon; Activates expression of the rhaSR operon in response to L- rhamnose.
 
  
 0.869
xylB
Xylulokinase; Similar to E. coli xylulokinase (AAC76588.1); Blastp hit to AAC76588.1 (484 aa), 85% identity in aa 1 - 484.
  
  
 0.810
fucO
Similar to E. coli L-1,2-propanediol oxidoreductase (AAC75841.1); Blastp hit to AAC75841.1 (383 aa), 91% identity in aa 2 - 383.
  
  
 0.795
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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