STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rhaBRhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family. (489 aa)    
Predicted Functional Partners:
rhaD
Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Belongs to the aldolase class II family. RhaD subfamily.
 
 0.999
rhaA
L-rhamnose isomerase. (SW:RHAA_SALTY).
 
 0.999
yiiL
Putative cytoplasmic protein; Involved in the anomeric conversion of L-rhamnose.
 
  
 0.965
araD
L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).
  
  
 0.958
araB
L-ribulokinase. (SW:KIRI_SALTY).
  
  
 0.957
rhaR
Positive regulator for rhaRS operon; Activates expression of the rhaSR operon in response to L- rhamnose.
 
  
 0.950
rhaT
DMT Superfamily L-rhamnose:H+ symporter protein; Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system); Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
 
  
 0.946
lyxK
Similar to E. coli L-xylulose kinase, cryptic (AAC76604.1); Blastp hit to AAC76604.1 (498 aa), 85% identity in aa 1 - 498.
   
 
0.930
rhaS
Positive regulator for rhaBAD operon; Activates expression of the rhaBAD and rhaT operons.
 
  
 0.918
rph
RNase PH; Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates.
      
 0.897
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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