STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rhaRPositive regulator for rhaRS operon; Activates expression of the rhaSR operon in response to L- rhamnose. (282 aa)    
Predicted Functional Partners:
rhaT
DMT Superfamily L-rhamnose:H+ symporter protein; Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system); Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
 
  
 0.969
melR
AraC/XylS family; similar to E. coli regulator of melibiose operon (AAC77079.1); Blastp hit to AAC77079.1 (302 aa), 88% identity in aa 4 - 302.
  
 
 0.945
rhaB
Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family.
 
  
 0.930
ydiP
Putative transcription regulator, AraC family; Similar to E. coli putative ARAC-type regulatory protein (AAC74766.1); Blastp hit to AAC74766.1 (303 aa), 80% identity in aa 1 - 292.
 
 
 0.895
STM4044
Putative iron-containing alcohol dehydrogenase; Similar to E. coli putative oxidoreductase (AAC76613.1); Blastp hit to AAC76613.1 (382 aa), 47% identity in aa 8 - 379.
  
  
 0.876
rhaA
L-rhamnose isomerase. (SW:RHAA_SALTY).
 
  
 0.869
pocR
Propanediol utilization protein; Positive regulatory protein of pdu and cob operons.
 
 
 0.827
marA
AraC/XylS family transcriptional activator of defense systems; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF.
  
 
 0.824
rhaD
Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Belongs to the aldolase class II family. RhaD subfamily.
  
  
 0.819
rob
Transcriptional regulator; AraC/XylS family; similar to E. coli right origin-binding protein (AAC77349.1); Blastp hit to AAC77349.1 (289 aa), 92% identity in aa 1 - 289.
 
   0.785
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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