Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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STM4068Putative gntR family regulatory protein; Similar to E. coli transcriptional regulator of succinylCoA synthetase operon (AAC73824.1); Blastp hit to AAC73824.1 (240 aa), 28% identity in aa 5 - 220. (240 aa)    
Predicted Functional Partners:
STM4065
Putative permease of the Na+:galactoside symporter family; Hypothetical protein (gi|7688349).
  
  
 0.981
gntR
Transcriptional repressor gnt-I; gntUKR; GalR/LacI family; similar to E. coli regulator of gluconate (gnt) operon (AAC76463.1); Blastp hit to AAC76463.1 (313 aa), 97% identity in aa 1 - 304.
  
  
 0.804
STM4067
Putative ADP-ribosylglycohydrolase; Similar to E. coli orf, hypothetical protein (AAC75160.1); Blastp hit to AAC75160.1 (334 aa), 30% identity in aa 108 - 325, 32% identity in aa 5 - 188.
    0.797
STM3602
Putative gntR family regulatory protein; Similar to E. coli putative transcriptional regulator (AAC76400.1); Blastp hit to AAC76400.1 (265 aa), 28% identity in aa 27 - 260.
  
  
 0.783
nadR
Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...]
   
  
 0.735
phnR
2-aminoethylphosphonate transport, repressor; Probable repressor protein of GntR family phnR (gi|11354257).
  
  
 0.716
STM4066
Putative sugar kinase; Ribokinase family; similar to E. coli putative kinase (AAD13445.1); Blastp hit to AAD13445.1 (300 aa), 28% identity in aa 14 - 297; Belongs to the carbohydrate kinase PfkB family.
  
    0.619
STM4069
Putative periplasmic protein.
  
    0.543
STM4070
Putative cytoplasmic protein; Similar to E. coli CDP-diacylglycerol phosphotidylhydrolase (AAC76900.1); Blastp hit to AAC76900.1 (251 aa), 81% identity in aa 214 - 250.
  
    0.538
ydiP
Putative transcription regulator, AraC family; Similar to E. coli putative ARAC-type regulatory protein (AAC74766.1); Blastp hit to AAC74766.1 (303 aa), 80% identity in aa 1 - 292.
  
    0.516
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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