STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
frwBSimilar to E. coli PTS system fructose-like IIB component 1 (AAC76932.1); Blastp hit to AAC76932.1 (106 aa), 96% identity in aa 1 - 106. (106 aa)    
Predicted Functional Partners:
frwC
Similar to E. coli PTS system, fructose-like enzyme II component (AAC76931.1); Blastp hit to AAC76931.1 (359 aa), 93% identity in aa 1 - 359.
  
 0.995
frwD
Similar to E. coli PTS system fructose-like IIB component 2 (AAC76935.1); Blastp hit to AAC76935.1 (113 aa), 83% identity in aa 3 - 113.
 
  
 
0.958
ptsA
General PTS family enzyme I; Similar to E. coli PEP-protein phosphotransferase system enzyme I (AAC76929.1); Blastp hit to AAC76929.1 (711 aa), 90% identity in aa 1 - 711.
 
  
 0.921
STM3256
Putative phosphotransferase system mannitol/fructose-specific IIA domain protein; Similar to E. coli PTS system, fructose-specific IIA/fpr component (AAC75230.1); Blastp hit to AAC75230.1 (376 aa), 52% identity in aa 3 - 141, 41% identity in aa 197 - 374.
 
  
 0.916
fruK
Similar to E. coli fructose-1-phosphate kinase (AAC75229.1); Blastp hit to AAC75229.1 (312 aa), 98% identity in aa 1 - 312; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.867
STM3254
Putative fructose-1-phosphate kinase; Similar to E. coli 6-phosphofructokinase II; suppressor of pfkA (AAC74793.1); Blastp hit to AAC74793.1 (309 aa), 27% identity in aa 4 - 291; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.863
fruF
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.
 
  
 0.815
pfkB
Similar to E. coli 6-phosphofructokinase II; suppressor of pfkA (AAC74793.1); Blastp hit to AAC74793.1 (309 aa), 92% identity in aa 1 - 308; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.739
STM4448
Putative phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
  
  
 0.643
ptsN
Sugar specific PTS family enzyme IIA; Also regulates N metabolism; similar to E. coli phosphotransferase system enzyme IIA, regulates N metabolism (AAC76236.1); Blastp hit to AAC76236.1 (163 aa), 95% identity in aa 1 - 163.
 
  
 0.639
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.