| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| STMF1.42 | birA | STM4141 | STM4138 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76953.1); Blastp hit to AAC76953.1 (51 aa), 55% identity in aa 1 - 40. | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.696 |
| STMF1.42 | coaA | STM4141 | STM4139 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76953.1); Blastp hit to AAC76953.1 (51 aa), 55% identity in aa 1 - 40. | Pantothenate kinase. (SW:COAA_SALTY). | 0.938 |
| STMF1.42 | hopD | STM4141 | STM3442 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76953.1); Blastp hit to AAC76953.1 (51 aa), 55% identity in aa 1 - 40. | Similar to E. coli leader peptidase, integral membrane protein (AAC76360.1); Blastp hit to AAC76360.1 (225 aa), 47% identity in aa 80 - 215; Belongs to the peptidase A24 family. | 0.767 |
| STMF1.42 | murB | STM4141 | STM4137 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76953.1); Blastp hit to AAC76953.1 (51 aa), 55% identity in aa 1 - 40. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation; Belongs to the MurB family. | 0.578 |
| STMF1.42 | tufB | STM4141 | STM4146 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76953.1); Blastp hit to AAC76953.1 (51 aa), 55% identity in aa 1 - 40. | Duplicate of tufA; elongation factor TU (EF-TU). (SW:EFTU_SALTY). | 0.716 |
| birA | STMF1.42 | STM4138 | STM4141 | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76953.1); Blastp hit to AAC76953.1 (51 aa), 55% identity in aa 1 - 40. | 0.696 |
| birA | coaA | STM4138 | STM4139 | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Pantothenate kinase. (SW:COAA_SALTY). | 0.791 |
| birA | murB | STM4138 | STM4137 | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation; Belongs to the MurB family. | 0.948 |
| coaA | STMF1.42 | STM4139 | STM4141 | Pantothenate kinase. (SW:COAA_SALTY). | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76953.1); Blastp hit to AAC76953.1 (51 aa), 55% identity in aa 1 - 40. | 0.938 |
| coaA | birA | STM4139 | STM4138 | Pantothenate kinase. (SW:COAA_SALTY). | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.791 |
| coaA | hopD | STM4139 | STM3442 | Pantothenate kinase. (SW:COAA_SALTY). | Similar to E. coli leader peptidase, integral membrane protein (AAC76360.1); Blastp hit to AAC76360.1 (225 aa), 47% identity in aa 80 - 215; Belongs to the peptidase A24 family. | 0.484 |
| hopD | STMF1.42 | STM3442 | STM4141 | Similar to E. coli leader peptidase, integral membrane protein (AAC76360.1); Blastp hit to AAC76360.1 (225 aa), 47% identity in aa 80 - 215; Belongs to the peptidase A24 family. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76953.1); Blastp hit to AAC76953.1 (51 aa), 55% identity in aa 1 - 40. | 0.767 |
| hopD | coaA | STM3442 | STM4139 | Similar to E. coli leader peptidase, integral membrane protein (AAC76360.1); Blastp hit to AAC76360.1 (225 aa), 47% identity in aa 80 - 215; Belongs to the peptidase A24 family. | Pantothenate kinase. (SW:COAA_SALTY). | 0.484 |
| murB | STMF1.42 | STM4137 | STM4141 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation; Belongs to the MurB family. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76953.1); Blastp hit to AAC76953.1 (51 aa), 55% identity in aa 1 - 40. | 0.578 |
| murB | birA | STM4137 | STM4138 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation; Belongs to the MurB family. | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.948 |
| tufB | STMF1.42 | STM4146 | STM4141 | Duplicate of tufA; elongation factor TU (EF-TU). (SW:EFTU_SALTY). | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76953.1); Blastp hit to AAC76953.1 (51 aa), 55% identity in aa 1 - 40. | 0.716 |