Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yjbAPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77000.1); Blastp hit to AAC77000.1 (136 aa), 87% identity in aa 1 - 136; Belongs to the PsiE family. (136 aa)    
Predicted Functional Partners:
eda
Multifunctional; similar to E. coli 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase (AAC74920.1); Blastp hit to AAC74920.1 (213 aa), 97% identity in aa 1 - 212; oxaloacetate decarboxylase.
      
 0.757
phoU
Regulatory gene for high affinity phosphate uptake; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.
      
 0.725
asr
Acid shock protein; Required for growth and/or survival at acidic conditions.
      
 0.719
STM3036
Putative inner membrane protein.
   
  
 0.718
phoE
Outer membrane pore protein e (e,ic,nmpab); Uptake of inorganic phosphate, phosphorylated compounds, and some other negatively charged solutes; Belongs to the Gram-negative porin family.
  
   
 0.698
apeE
Outer membrane N-acetyl phenylalanine beta-naphthyl ester-cleaving esterase; Outer membrane esterase (gi|2896133).
      
 0.679
iciA
Inhibitor of replication initiation; Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family.
      
 0.651
yjbF
Putative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC76997.1); Blastp hit to AAC76997.1 (222 aa), 86% identity in aa 1 - 221.
      0.647
yjbG
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76998.1); Blastp hit to AAC76998.1 (245 aa), 74% identity in aa 1 - 245.
      0.638
phoH
Similar to E. coli PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation (AAC74105.1); Blastp hit to AAC74105.1 (354 aa), 92% identity in aa 71 - 354.
      
 0.635
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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