Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
STM4260Membrane permease; Predicted cation efflux pump; HLYD secretion protein (gi|7467244). (425 aa)    
Predicted Functional Partners:
STM4259
ABC exporter outer membrane component homolog (gi|7467234).
 
 
 0.999
STM4261
Putative inner membrane protein; Fusion of two hypothetical proteins; (gi|7467255) and (gi|7467255).
 
  
 0.998
STM4262
Putative ABC-type bacteriocin/lantibiotic exporter; Contains an N-terminal double-glycine peptidase domain; leukotoxin expression protein B homolog (gi|7467272).
 
 
 0.993
STM4258
Putative methyl-accepting chemotaxis protein; Hypothetical protein spi4_A (gi|7467268).
  
    0.941
STM4257
Putative inner membrane or exported; Hypothetical protein spi4_A (gi|7467268).
  
    0.868
invJ
Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the SpaN family.
   
    0.857
STM2691
Putative ABC transporter transmembrane region; Similar to E. coli ATP-binding transport protein; multicopy suppressor of htrB (AAC74000.1); Blastp hit to AAC74000.1 (582 aa), 26% identity in aa 20 - 557.
 
 
 
 0.828
invC
Surface presentation of antigens; Necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase. May energize the protein export apparatus encoded in the inv locus which is required for the surface presentation of determinants needed for the entry of salmonella species into mammalian cells.
   
    0.828
invI
Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells.
   
    0.752
prgH
Cell invasion protein; Required for invasion of epithelial cells.
   
    0.743
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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