STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM4261Putative inner membrane protein; Fusion of two hypothetical proteins; (gi|7467255) and (gi|7467255). (5559 aa)    
Predicted Functional Partners:
STM4260
Membrane permease; Predicted cation efflux pump; HLYD secretion protein (gi|7467244).
 
  
 0.998
STM4262
Putative ABC-type bacteriocin/lantibiotic exporter; Contains an N-terminal double-glycine peptidase domain; leukotoxin expression protein B homolog (gi|7467272).
 
  
 0.991
STM4259
ABC exporter outer membrane component homolog (gi|7467234).
  
  
 0.984
yhgE
Putative inner membrane protein; Similar to E. coli putative transport (AAC76427.1); Blastp hit to AAC76427.1 (574 aa), 56% identity in aa 1 - 574.
      
 0.894
STM4258
Putative methyl-accepting chemotaxis protein; Hypothetical protein spi4_A (gi|7467268).
  
    0.893
invC
Surface presentation of antigens; Necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase. May energize the protein export apparatus encoded in the inv locus which is required for the surface presentation of determinants needed for the entry of salmonella species into mammalian cells.
  
  
 0.826
pgtB
Protein for signal transmission; Member of the two-component regulatory system PgtB/PgtA that regulates the inducible phosphoglycerate transport system. Activates PgtA by phosphorylation.
      
 0.765
spaS
Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the type III secretion exporter family.
  
  
 0.758
invJ
Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the SpaN family.
   
    0.751
STM4257
Putative inner membrane or exported; Hypothetical protein spi4_A (gi|7467268).
  
    0.750
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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