STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yjcDPutative xanthine/uracil permease family; Similar to E. coli orf, hypothetical protein (AAC77034.1); Blastp hit to AAC77034.1 (449 aa), 97% identity in aa 1 - 449. (449 aa)    
Predicted Functional Partners:
yicE
Similar to E. coli putative transport protein (AAC76678.1); Blastp hit to AAC76678.1 (463 aa), 95% identity in aa 1 - 462.
 
  
 0.951
yjcE
Putative CPA1 family Na:H transport protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
 
    0.819
purG
Phosphoribosylformylglycinamidine synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.810
yieG
Putative xanthine/uracil permeases family; Similar to E. coli putative membrane / transport protein (AAC76737.1); Blastp hit to AAC76737.1 (445 aa), 96% identity in aa 1 - 445.
  
   
0.746
purK
Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, CO(2)-fixing subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
    0.665
purT
Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
   
    0.661
uraA
NCS2 family uracil transport protein; Similar to E. coli uracil transport (AAC75550.1); Blastp hit to AAC75550.1 (429 aa), 94% identity in aa 1 - 425.
 
  
 0.657
STM3333
Putative purine-cytosine permease; Similar to E. coli cytosine permease/transport (AAC73439.1); Blastp hit to AAC73439.1 (419 aa), 82% identity in aa 1 - 414.
  
  
 0.643
purD
GAR synthetase; phosphoribosylamine--glycine ligase. (SW:PUR2_SALTY); Belongs to the GARS family.
  
  
 0.625
purE
Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
    0.606
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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