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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yjcEPutative CPA1 family Na:H transport protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (548 aa)    
Predicted Functional Partners:
nhaA
NhaA family of transport protein, Na+/H antiporter, pH dependent; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
  
  
 0.928
yjcD
Putative xanthine/uracil permease family; Similar to E. coli orf, hypothetical protein (AAC77034.1); Blastp hit to AAC77034.1 (449 aa), 97% identity in aa 1 - 449.
 
    0.806
chaA
Similar to E. coli sodium-calcium/proton antiporter (AAC74300.1); Blastp hit to AAC74300.1 (366 aa), 93% identity in aa 1 - 366.
    
 
 0.800
nhaR
LysR family; similar to E. coli transcriptional activator of nhaA (AAC73131.1); Blastp hit to AAC73131.1 (301 aa), 92% identity in aa 1 - 296; Belongs to the LysR transcriptional regulatory family.
      
 0.767
STM1559
Putative glycosyl hydrolase; Similar to E. coli trehalase 6-P hydrolase (AAC77196.1); Blastp hit to AAC77196.1 (551 aa), 36% identity in aa 41 - 129, 25% identity in aa 149 - 210, 37% identity in aa 356 - 379.
  
  
 0.514
hutG
Formimionoglutamate hydrolase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
   
  
 0.463
ycgO
Putative CPA1 family Na:H transport protein; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
      
 0.459
yrbG
Putative CacA family Na:Ca transport protein; Similar to E. coli orf, hypothetical protein (AAC76228.1); Blastp hit to AAC76228.1 (325 aa), 87% identity in aa 1 - 324.
   
 
 0.459
kefC
CPA2 family K+ efflux antiporter, glutathione-regulated; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
  
 
 0.449
kefB
CPA2 family K+:H+ antiporter; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
  
 
 0.449
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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