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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM4270Putative LysR family transcriptional regulator; Similar to E. coli activator, hydrogen peroxide-inducible genes (AAC76943.1); Blastp hit to AAC76943.1 (305 aa), 28% identity in aa 1 - 275; Belongs to the LysR transcriptional regulatory family. (295 aa)    
Predicted Functional Partners:
STM4271
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75202.1); Blastp hit to AAC75202.1 (132 aa), 33% identity in aa 13 - 113.
 
    0.890
STM4272
Putative inner membrane protein; Similar to E. coli putative seritonin transporter (AAC75203.1); Blastp hit to AAC75203.1 (231 aa), 36% identity in aa 9 - 222.
 
    0.760
yifA
Putative LysR family transcriptional regulator; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
  
     0.748
STM3020
Similar to E. coli putative transcriptional regulator LYSR-type (AAC73606.1); Blastp hit to AAC73606.1 (308 aa), 26% identity in aa 2 - 275; Belongs to the LysR transcriptional regulatory family.
  
    0.742
lrhA
Similar to E. coli NADH dehydrogenase transcriptional regulator, LysR family (AAC75349.1); Blastp hit to AAC75349.1 (312 aa), 86% identity in aa 1 - 312; Belongs to the LysR transcriptional regulatory family.
  
     0.717
ydhB
Similar to E. coli putative transcriptional regulator LYSR-type (AAC74731.1); Blastp hit to AAC74731.1 (310 aa), 90% identity in aa 1 - 310; Belongs to the LysR transcriptional regulatory family.
  
    0.635
STM0764
Similar to E. coli putative transcriptional regulator LYSR-type (AAC77283.1); Blastp hit to AAC77283.1 (303 aa), 30% identity in aa 9 - 300; Belongs to the LysR transcriptional regulatory family.
  
     0.602
STM0333
Similar to E. coli putative transcriptional regulator LYSR-type (AAC74869.1); Blastp hit to AAC74869.1 (314 aa), 44% identity in aa 2 - 307; Belongs to the LysR transcriptional regulatory family.
  
    0.593
yjiE
Similar to E. coli putative transcriptional regulator LYSR-type (AAC77283.1); Blastp hit to AAC77283.1 (303 aa), 81% identity in aa 1 - 302; Belongs to the LysR transcriptional regulatory family.
  
     0.508
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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