STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrfANitrite reductase periplasmic cytochrome c(552); Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family. (478 aa)    
Predicted Functional Partners:
nrfD
Similar to E. coli formate-dependent nitrate reductase complex; transmembrane protein (AAC77043.1); Blastp hit to AAC77043.1 (318 aa), 85% identity in aa 1 - 318.
 
 
 0.997
nrfC
Fe-S centers; similar to E. coli formate-dependent nitrite reductase; Fe-S centers (AAC77042.1); Blastp hit to AAC77042.1 (223 aa), 91% identity in aa 1 - 223.
 
 
 0.995
nrfB
Formate-dependent nitrite reductase; A penta-haeme cytochrome c; similar to E. coli formate-dependent nitrite reductase; a penta-haeme cytochrome c (AAC77041.1); Blastp hit to AAC77041.1 (190 aa), 88% identity in aa 1 - 190.
 
  
 0.994
hcp
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
 
  
 0.983
napA
Periplasmic large subunit nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
   
 
 0.983
narG
Similar to E. coli nitrate reductase 1, alpha subunit (AAC74308.1); Blastp hit to AAC74308.1 (1247 aa), 95% identity in aa 1 - 1247; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
 
 0.981
nirB
Similar to E. coli nitrite reductase (NAD(P)H) subunit (AAC76390.1); Blastp hit to AAC76390.1 (847 aa), 95% identity in aa 1 - 847; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.980
nrfE
Formate-dependent nitrite reductase; Possible subunit of a heme lyase.
 
  
 0.980
nrfG
Involved in attachment of haem c to cytochrome c552; similar to E. coli part of formate-dependent nitrite reductase complex (AAD13459.1); Blastp hit to AAD13459.1 (198 aa), 71% identity in aa 6 - 196.
 
  
 0.976
nirD
Nitrite reductase small subunit; Required for activity of the reductase.
   
 
 0.958
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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