STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM4302Putative cytoplasmic protein. (88 aa)    
Predicted Functional Partners:
STM4309
Putative periplasmic or exported protein.
   
  
 0.954
tnpA_6
Transposase for insertion sequence element IS200 (SW:T200_SALTY).
      
 0.897
tnpA_1
IS200 transposase; Involved in the transposition of the insertion sequence.
      
 0.726
STM4312
Putative phage protein.
   
  
 0.652
dcuB
Dcu family anaerobic C4-dicarboxylate transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
  
    0.531
dcuR
Response regulator in two-component regulatory system with DcuS; Regulates anaerobic fumarate respiration; similar to E. coli putative 2-component transcriptional regulator (AAC77085.1); Blastp hit to AAC77085.1 (239 aa), 88% identity in aa 1 - 239.
  
    0.424
dcuS
Sensory histidine kinase in two-component retgulatory system with DcuR; Senses fumarate/C4-dicarboxylate; similar to E. coli putative 2-component sensor protein (AAC77086.1); Blastp hit to AAC77086.1 (543 aa), 81% identity in aa 1 - 542.
  
    0.409
fumB
Fumarase B; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
    0.402
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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